心房会加速老年人的功能衰退:一项为期15年的基于人口的随访研究
Chukwuma Okoye1,2,3, Chengxuan Qiu1, Xin Xia4
1Aging Research Center, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm University, Tomtebodavägen 18a, 171 65 Solna, Sweden.
概括
患有心房动 (AF) 的老年人经历了步行速度 (WS) 的更快下降. 诸如心力衰竭和中风等疾病可能会使AF患者的功能性移动性丧失恶化.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 与功能障碍有关.
- AF对功能性移动性轨迹的长期影响尚未完全理解.
研究的目的:
- 调查AF对功能移动性的影响.
- 为了分析60岁以上的个体15年的步行速度 (WS) 轨迹.
主要方法:
- 对3141名老年人的基于人口的队列研究 (瑞典国家老龄化和护理研究在Kungsholmen).
- 在15年 (2001-2019) 期间对WS进行了纵向评估.
- 用于分析AF与WS衰退的关联的多变量联合模型,考虑放弃学业.
主要成果:
- 9.1%的参与者在基线时有AF.
- 患有AF的个体显示每年WS下降速度更快 (调整后β=-0.011).
- 发生心力衰竭和中风加速了AF参与者的WS下降;口服抗凝剂治疗没有减缓下降.
结论:
- 心房动与老年人的加速身体功能下降有关.
- 随着时间的推移,心力衰竭和中风可能会加剧AF患者的步行速度下降.
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