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Updated: Jun 23, 2025

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同种植物素通过与TAK1结合来阻断NF-κB/MAPK通路来缓解椎间盘退化

Baixing Li1, Yibin Hu1, Yan Chen1

  • 1Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China.

Biochemical pharmacology
|June 24, 2024
PubMed
概括

同类植物素 (Hom) 在治疗椎间盘退化症 (IVDD) 方面表现有前途. 这种化合物通过抑制关键信号通路来缓解炎症并恢复细胞外矩阵平衡,从而有可能在腰部疼痛 (LBP) 中进行早期干预.

关键词:
同种植物中的同种植物.炎症 炎症是一种炎症.椎间盘退化 椎间盘退化通过NF-κB/MAPK信号通路传递信号.这就是TAK1的意义.

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