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Updated: Jun 23, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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Published on: August 23, 2019

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VHL抑制了UBE3B介导的乳腺瘤生长和转移

Shuo Wang1, Huiyan Li1, Xiong Liu2

  • 1Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Institute of Biomedical Science, College of Life Sciences, Shandong Normal University, Jinan, Shandong, 250014, China.

Cell death & disease
|June 24, 2024
PubMed
概括

希佩尔-林道 (VHL) 蛋白作为瘤蛋白UBE3B的E3结合酶,准其降解. 这种VHL-UBE3B相互作用抑制了乳腺癌的生长和转移.

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