牛皮和喘之间的关联:系统审查和双向元分析
Doudou Wu1, Xiangnan Zhou2, Fan Wu1
1Department of Integrative Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Beijing, China.
BMC pulmonary medicine
|June 24, 2024
概括
牛皮患者患喘的风险增加了48%,而喘患者患牛皮的风险增加了33%. 这种双向联系凸显了提高意识的必要性,特别是在青少年和严重牛皮患者中.
科学领域:
- 皮肤病学和肺病学
- 流行病学 流行病学
- 系统性审查和元分析
背景情况:
- 以前的研究表明牛皮和喘之间存在联系,但双向关系需要进一步探索.
- 这项研究解决了充分理解这两个条件之间的关联的需要.
研究的目的:
- 为了调查牛皮和喘之间的双向关联.
- 在牛皮患者中量化发展喘的风险,反之亦然.
主要方法:
- 在PubMed,Embase和Cochrane图书馆进行了全面的系统文献搜索,直到2023年10月.
- 对16项涉及12,396,911名参与者的观察性研究进行了元分析,使用基于异质性的固定或随机效应模型进行了分析.
- 出版偏差是使用漏斗图和埃格尔测试来评估的.
主要成果:
- 牛皮患者患喘的风险显著增加 (OR = 1.48,95% CI 1.28-1.68).
- 喘患者也表现出明显更高的患上牛皮的风险 (OR = 1.33,95% CI 1.23-1.44).
- 小组分析表明,研究类型,年龄和牛皮的严重程度影响了牛皮患者的喘风险.
结论:
- 牛皮和喘之间存在着显著的双向关联.
- 临床医生应该教育患者,特别是青少年和中度至重度牛皮患者,了解患上另一种疾病的风险增加.
相关概念视频
Asthma-II: Pathophysiology and Classification
2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Asthma: Pathogenesis and Management
384
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
384
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
270
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
270


