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5岁以下儿童疟疾:非洲高风险国家的流行率和多因素分析
Jackline Vicent Mbishi1, Suleiman Chombo2, Pankras Luoga2
1Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania. jvmbishi94@gmail.com.
BMC public health
|June 24, 2024
概括
疟疾影响了撒哈拉以南非洲5岁以下儿童的26.2%. 母亲教育和家庭财富显著降低了儿童疟疾风险,而农村生活则增加了疟疾风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 疟疾仍然是撒哈拉以南非洲 (SSA) 的关键公共卫生问题,不成比例地影响到五岁以下的儿童 (联合国5).
- 尽管全球控制努力,但高发病率和死亡率仍然存在,需要更深入地了解导致因素.
- 确定各种儿童,母亲和家庭特征与疟疾患病率之间的关联对于有效的干预至关重要.
研究的目的:
- 确定高风险SSA国家的UN5儿童中疟疾的流行率.
- 分析童年,母性和家庭因素与疟疾在这个脆弱群体的流行率之间的关联.
主要方法:
- 分析了来自7个高流行率SSA国家35,624名UN5儿童的加权数据 (2010-2023年疟疾指标调查).
- 用描述性统计和修改的波桑回归来评估因子关联.
- 统计学意义在5%的水平上确定,使用Stata 15.
主要成果:
- 在联合国5国儿童中,结合的疟疾患病率为26.2%,在各国之间存在显著差异.
- 与较低疟疾风险相关的因素包括更高的孕产妇教育和怀孕期间使用Fansidar.
- 来自富裕家庭和城市住宅的儿童与来自贫困家庭和农村地区的儿童相比,疟疾患病率较低.
结论:
- 在SSA的UN5儿童中疟疾的患病率受到母亲教育,怀孕干预,社会经济地位和居住地的影响.
- 针对这些决定因素的有针对性的预防策略对于减少疟疾负担至关重要.
- 研究结果强调,需要采用综合方法,在脆弱的年轻人群中打击疟疾.
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