心房动和与癌症相关的缺血性中风后的短期结果
Farah Wahbeh1, Cenai Zhang1, Morin Beyeler1
1Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY, USA.
European stroke journal
|June 25, 2024
概括
患有癌症和急性缺血性中风 (AIS) 的患者,同时也患有心房动 (AF),面临更糟糕的结果. 这包括更高的住院死亡率,更长的住院时间,以及增加非家庭出院的可能性.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 在瘤学瘤学.
背景情况:
- 心房动 (AF) 和癌症独立地恶化了急性缺血性中风 (AIS) 患者的结果.
- 有限的研究存在于AF和癌症对中风结果的综合影响.
研究的目的:
- 调查伴随性心房 (AF) 与急性缺血性中风 (AIS) 和癌症住院患者的短期结果之间的关联.
- 确定AF是否独立预测该患者群体的住院死亡率,住院时间和出院倾向.
主要方法:
- 使用2016-2019年全国住院患者样本进行的回顾性横截面研究.
- 纳入标准:住院患者的诊断代码包括癌症和AIS.
- 统计分析涉及多变量逻辑和线性回归,调整人口统计因素和并发症.
主要成果:
- 这项研究分析了150,200例因癌症和AIS住院病例;26.7%患有并发性AF.
- 患有AF的住院患者的住院死亡率显著增加 (14.8%与12.1%相比),平均住院时间更长 (8.4与8.2天),非家庭出院率增加 (83.5%与75.1%相比).
- 多变量分析证实AF是死亡率较高 (aOR1.34),非家庭出院 (aOR1.32) 和住院时间较长 (13.7%的增加) 的独立预测因素.
结论:
- 同病性心房 (AF) 与癌症相关的急性缺血性中风 (AIS) 患者的短期结果明显恶化有关.
- 这些不良结果包括增加住院死亡率,更高的离家出院率,以及长时间住院治疗.
- 这些发现强调了AF对患有AIS的癌症患者预后的关键影响.
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