韩国儿科患有喉支气管支气管炎的儿童抗生素:基于行政数据的全国性研究
Seung Beom Han1,2, Kil Seong Bae1,3, Ui Yoon Choi1,3,4
1Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Journal of Korean medical science
|June 25, 2024
概括
在韩国,对儿科的不必要的抗生素处方很常见,特别是在医院和诊所. 抗微生物药物管理计划应针对这些环境中的医生,以打击抗微生物药物耐药性 (AMR).
科学领域:
- 儿童传染病 儿童传染病
- 抗微生物药物管理管理
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 喉支骨支骨炎 (),一个常见的儿童呼吸道感染,通常是病毒性,不需要抗生素.
- 通过抗微生物管理计划 (ASP) 减少急性呼吸道感染 (ARIs) 中不必要的抗生素使用对于对抗儿童抗菌耐药性至关重要.
研究的目的:
- 调查在韩国被诊断患有喉外支气管炎的儿科患者的抗生素处方模式.
- 为了确定与这种情况的抗生素处方相关的因素.
- 为改善韩国儿科抗菌药物管理计划 (ASP) 提供数据.
主要方法:
- 对年龄在5岁以下的儿童的门诊处方的分析,其中包括国际疾病分类第10次修订的喉支气管支气管炎的代码 (J050,J040,J041) 从2017年至2020年.
- 提取每个处方的人口统计和医疗机构信息.
- 估计了总体抗生素处方率,并进行了多变量分析以确定相关因素.
主要成果:
- 在2,358,194份处方中,35.2%包括抗生素.
- 医院管理 (aOR, 22.33) 和诊所管理 (aOR, 12.66) 与抗生素处方有很强的联系.
- 较年轻的儿童 (≤2岁),儿科专家看的儿童以及非大都市地区的抗生素使用率较高. 扩展谱的青素是最常见的.
结论:
- 抗菌药物管理计划 (ASP) 应优先考虑医院,诊所和儿科专业的医生.
- 针对这些群体的教育干预措施可以提高对抗药性耐药性和适当使用抗生素的认识.
- 这些策略可以有效地减少对儿科喉支气管支气管炎的不必要的抗生素处方,从而减轻韩国儿童的AMR.
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