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Updated: Jun 23, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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双重向KDM1A和抗氧化剂是一种有效的抗癌策略

Shaila Mudambi1,2, Megan E Fitzgerald1,2, Deschana L Washington1

  • 1Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, United States 14263.

bioRxiv : the preprint server for biology
|June 25, 2024
PubMed
概括

抑制氨酸特异性脱甲酶1 (KDM1A) 通过影响缺氧诱导因子1A (HIF-1A) 和谷氨水平,增加了癌细胞对氧化应激的敏感性. 这表明KDM1A抑制剂与抗氧化剂消耗疗法相结合,可以提供一种新的抗癌策略.

关键词:
这就是HIF-1A.在KDM1A中,KDM1A是KDM1A.抗氧化剂 抗氧化剂是一种抗氧化剂.癌症 癌症 癌症 癌症 癌症有活性氧物种的反应性氧物种.

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