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Updated: Jun 23, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

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缺少Akt2会损害Th17的分化,增加Th2的分化,并改变对免疫接种的外周反应

Lauren B Banks, Tammarah Sklarz, Mercy Gohil

    bioRxiv : the preprint server for biology
    |June 25, 2024
    PubMed
    概括

    氨酸三氨酸激酶Akt异型,Akt1和Akt2,对于T细胞分化至关重要. Akt2在调节外围CD4T细胞反应方面发挥着重要作用,影响Th17分化和细胞因子产生.

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