使用分裂-Ugi反应合成可离子化脂聚合物,用于肺部输送各种大小的RNA和基因编辑

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Updated: Jun 23, 2025

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Published on: February 1, 2019

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K Yu Vlasova, A Kerr, N D Pennock

    bioRxiv : the preprint server for biology
    |June 25, 2024
    PubMed
    概括

    研究人员开发了用于高效的mRNA输送的新型阴阳性脂聚合物,显示了肺向和治疗癌症和囊性纤维化模型的治疗结果的显著改善,毒性低.

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