Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

416
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
416
Anatomy of the Intestines01:23

Anatomy of the Intestines

71.7K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.7K
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

71.1K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Risk factors associated with secondary displacement in fractures of the humeral greater tuberosity.

Frontiers in surgery·2025
Same author

Treatment of lumbar spondylolysis in young adults using modified intravertebral screw-rod fixation system for single vertebral body combined with autologous cancellous bone graft: a technical note and preliminary report.

Journal of orthopaedic surgery and research·2024
Same author

Identification and experimental validation of programmed cell death- and mitochondria-associated biomarkers in osteoporosis and immune microenvironment.

Frontiers in genetics·2024
Same author

Diapause-like Drug-Tolerant Persister State: The Key to Nirvana Rebirth.

Medicina (Kaunas, Lithuania)·2024
Same author

Successful diagnosis by capsule endoscopy of small intestinal ascariasis that had been misdiagnosed repeatedly.

Gastrointestinal endoscopy·2023
Same author

The role of vitamin D through SphK1/S1P in the regulation of MS progression.

The Journal of steroid biochemistry and molecular biology·2023

相关实验视频

Updated: Jun 23, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.9K

结直肠粘膜和便之间的微生物组组成和功能差异.

Xiao-Fei Yin1, Taoyu Ye2, Han-Lin Chen1

  • 1Department of Gastroenterology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.

Microbiology spectrum
|June 25, 2024
PubMed
概括

这项研究揭示了直肠粘膜和便之间的明显肠道微生物群差异,在患有结肠多的患者中. 粘膜微生物组表现出独特的组成和途径,为结直肠癌风险提供了洞察力.

关键词:
凯格正统诊所的正统诊所 (KEGG Orthology) 是一个正统诊所.差异标记器的差异标记器我们的肠道微生物组.大基因组测序的测序.这是直肠粘膜.

更多相关视频

Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans
07:19

Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans

Published on: September 13, 2022

2.2K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.2K

相关实验视频

Last Updated: Jun 23, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.9K
Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans
07:19

Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans

Published on: September 13, 2022

2.2K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.2K

科学领域:

  • 微生物组研究的研究.
  • 肠道健康 肠道健康
  • 结肠直肠癌的发病因子

背景情况:

  • 以前的肠道微生物组研究主要使用便样本,忽视了肠道粘膜微生物组.
  • 居住在直肠粘膜上的微生物群落仍然相对未被探索,造成了知识差距.

研究的目的:

  • 综合地绘制和比较直肠粘膜中的微生物群落与匹配的便样本.
  • 研究直肠粘膜的独特微生态特征及其与结直肠癌风险因素的关联.
  • 为了确定潜在的肠道微生物群生物标志物对健康和疾病状态.

主要方法:

  • 枪支元基因组学被用来分析微生物的组成.
  • 样本包括正常的直肠粘膜和来自20名结肠多患者的匹配便.
  • 使用KEGG Orthology (KO) 标注来探索功能途径.

主要成果:

  • 在粘膜和便微生物组之间观察到显著的区别.
  • 粘膜微生物组表现出较少的属,Burkholderia是关键的区分属.
  • 与年龄相关的新生物标志物,包括Clostridium ramosum和Enterobacter cloacae被确定.
  • 在粘膜微生物群中观察到与糖运输和短链脂肪酸代谢相关的途径的丰富.

结论:

  • 直肠粘膜微生物组具有独特的特征,与便微生物组不同.
  • 这些发现突显了肠道微生物群落的特异性及其在结直肠癌中的潜在作用.
  • 这项研究为开发新的基于微生物组的结直肠癌预防和治疗策略提供了基础.