菌根素welchii疫苗粒瘤 - 一个警告故事
C Anju George1, Satyaki Ganguly2, Ajoy Kumar Behera3
1Department of Dermatology, Aster Medcity, Kochi, Kerala, India.
International journal of mycobacteriology
|June 25, 2024
概括
用于预防COVID-19的mycobacteriumw疫苗可以导致注射部位颗粒瘤. 治疗包括抗炎药物和抗生素,在最近的一项研究中没有报告复发.
科学领域:
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 微细菌welchii (Mycobacterium w) 疫苗被探索用于COVID-19的预防和治疗.
- 一项回顾性分析确定了15例疫苗部位颗粒瘤的病例,这些病例是在Mycobacterium w的管理后出现的.
研究的目的:
- 为了分析Mycobacterium在COVID-19预防后疫苗部位颗粒瘤的病例.
- 报告这些细粒瘤病例的管理和结果.
主要方法:
- 对接受了Mycobacterium w疫苗的15名患者的回顾性分析.
- 临床观察和诊断工作,包括皮肤活检.
- 对治疗反应的评估.
主要成果:
- 15名患者在一个月内在注射部位出现了柔软的结节.
- 活检显示颗粒状皮肤炎与阳性酸性细菌;培养是负的.
- 诊断为非传染性粒状皮炎; 9/15需要全身抗生素.
结论:
- 注射部位颗粒瘤是Mycobacteriumw疫苗的潜在风险,需要风险效益评估和患者咨询.
- 持续性反应对多西环林,奥洛素和克拉里思罗米的组合.
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