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Updated: Jun 20, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
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In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis

Published on: May 4, 2017

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蒂克萨吉维玛布-奇尔加维玛布的真实世界有效性和安全性:一个目标试验仿真研究

Vincent Ka Chun Yan1, Yu Yang1, Eric Yuk Fai Wan1,2,3

  • 1Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.

Drug safety
|June 25, 2024
PubMed
概括

在Omicron浪潮期间,Tixagevimab-cilgavimab有效地减少了免疫力低下个体的COVID-19感染. 这种单克隆抗体治疗显示出显著的保护,即使在那些先前接种疫苗或没有感染史的人中也是如此.

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Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

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In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells

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相关概念视频

Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...