癌症相关疲劳的定义,评估和维度:一个范围审查
Kayla F Keane1, Jordan Wickstrom2,3, Alicia A Livinski4
1National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.
概括
与癌症相关的疲劳 (CRF) 缺乏普遍的定义和评估方法. 本次审查强调了需要标准化的方法,以更好地了解和管理全球癌症患者的CRF.
科学领域:
- 在瘤学瘤学.
- 患者护理 患者护理
- 研究方法研究方法研究方法学
背景情况:
- 癌症相关疲劳 (CRF) 在临床实践中存在重大挑战,原因是定义和评估工具不一致.
- 缺乏共识阻碍了对患有CRF的患者进行有效的诊断和管理策略.
研究的目的:
- 进行范围审查,以综合癌症相关疲劳 (CRF) 如何在全球范围内定义和评估成人癌症患者.
- 在各种研究研究中确定CRF定义和测量的共同点和差异.
主要方法:
- 在四个主要数据库 (PubMed,Embase,CINAHL Plus,PsycNet) 进行了全面的搜索,查找2010年至2020年间发表的原创研究文章.
- 如果CRF是主要结果,则将文章纳入其中,并将其描述为一个维度构造,由独立审稿人严格选和数据提取.
- 总共有2923篇文章被选,最终包括150篇在审查中.
主要成果:
- 只有68%的纳入研究提供了CRF的定义,90%将其描述为多维;41%符合国家综合癌症网络的定义.
- 大多数研究是在美国进行的,采用了定量,纵向和观察设计,并专注于接受化疗的乳腺癌患者.
- 主要使用的是多维测量 (97%),多维疲劳库存 (MFI-20) 是最常见的,而"身体"疲劳是最常见的报告维度.
结论:
- 审查强调了对CRF普遍接受的定义的关键需求.
- 评估工具的标准化对于在研究和临床环境中一致和可靠地测量CRF至关重要.
- 建立共识将改善疲劳的癌症患者的诊断,管理和整体护理.
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