三合体植入物的大动脉面积指数值与能量损失和增加的门应力相关
Toru Tsukada1, Yasuyuki Suzuki2, Bryan J Mathis1
1Department of Cardiovascular Surgery, University of Tsukuba Institute of Medicine, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
概括
与Inspiris相比,Trifecta生物在运动期间显示出大动脉膜面积的更大变化. 这表明三合一门可能会经历更高的应力和更快的磨损.
科学领域:
- 心血管外科心血管外科
- 生物医学工程 生物医学工程
- 诊断成像 诊断成像 诊断成像
背景情况:
- 生物门越来越多地用于大动脉门置换 (AVR).
- 对于生物门在运动压力期间的心声回声学研究有限.
- 在运动负荷下对大动脉膜面积 (AVA) 动态变化的比较研究很少.
研究的目的:
- 为了比较Trifecta和Inspiris生物门在运动压力心声学期间对大动脉膜面积 (AVA) 的变化速率.
- 用四维流磁共振成像 (4D流MRI) 来评估静止状态的水力动力性能.
主要方法:
- 在AVR后的患者进行了运动应激回声心电图,使用Trifecta (n=7) 或Inspiris (n=7) 门.
- 四维流MRI被用于静止状态的水力动力学分析.
- 从休息到25W负载的AVA的百分比变化被计算出来.
主要成果:
- 在运动负载下,三合一门在AVA (28.7%) 的百分比变化明显高于Inspiris门 (-0.8%).
- 三合一门在静止状态下显示出较高的缩能量损失 (97.5mW),而不是Inspiris门 (52.7mW),通过4D流MRI.
- 在Trifecta门中较小的静止AVA可能导致观察到的差异.
结论:
- 三合一门的设计可能会导致休息时的开放受限,并且由于门应力较高,可能会更快地磨损.
- 这些发现可能与早期需要重新操作的Trifecta退化报告相关.
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