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Updated: Jun 23, 2025

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物质P调节记忆Th17细胞的生成和维护,在慢性干眼疾病中

Shudan Wang1,2, Amirreza Naderi1, Francesca Kahale1

  • 1Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, United States.

Journal of leukocyte biology
|June 25, 2024
PubMed
概括

物质P通过促进致病性Th17细胞驱动慢性干眼病. 阻止其受体,神经素1,通过准这些记忆Th17细胞,提供了一种治疗眼睛表面炎症的新策略.

关键词:
慢性炎症是一种慢性炎症.记忆 CD4+ T 细胞神经基因素1受体的受体

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相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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