欧洲新生儿单位的抗真菌药物使用:多中心每周点发病率研究
Elisavet Chorafa1, Elias Iosifidis1, Andrea Oletto2
1From the Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
The Pediatric infectious disease journal
|June 25, 2024
概括
欧洲新生儿病房的抗真菌使用主要用于预防和经验治疗. 可纳是最常见的抗真菌药物,用于预防和治疗新生儿.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 关于新生儿群体的抗真菌处方模式的数据有限.
- 以前的研究往往是单个中心,单个国家或短期的.
- 欧洲新生儿单位的纵向抗真菌使用数据很少.
研究的目的:
- 评估欧洲新生儿单位 (NU) 系统性抗真菌药物的纵向使用情况.
- 确定在多个欧洲国家的新生儿处方抗真菌药物的模式和说明.
- 提供当前新生儿护理中抗真菌药物使用情况的全面概述.
主要方法:
- 一个前性的,每周点患病率研究 (CALYPSO) 在2020年进行了12周.
- 从8个欧洲国家的27个新生儿病房收集了数据.
- 收集的信息包括病房人口统计,患者数据,适应症,危险因素和抗真菌疗法.
主要成果:
- 抗真菌预防在56%的NU中进行,主要针对有风险因素的早产婴儿.
- 平均10.5%的新生儿每周接受抗真菌药物.
- 可纳是最常用于预防 (78%) 和治疗 (39%) 的全身性药物.
结论:
- 欧洲国家药区的抗真菌处方主要用于预防和经验治疗.
- 可纳是新生儿预防和治疗目的的主要抗真菌剂.
- 该研究强调了预防在新生儿抗真菌使用模式中的重要作用.
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