睡眠在大麻使用和记忆功能之间的联系中的作用:来自横截面研究的证据
T Brown1, R A Ackerman1, E Kroon2,3
1Department of Psychology, School of Behavioral and Brain Sciences, University of Texas at Dallas, Dallas, Texas, USA.
The American journal of drug and alcohol abuse
|June 25, 2024
概括
大麻使用障碍 (CUD) 与较差的记忆有关,睡眠质量作为关键调解者. 解决睡眠问题可能对改善CUD患者的记忆力至关重要.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
背景情况:
- 大麻使用独立地影响记忆和睡眠.
- 大麻引起的睡眠问题和记忆力缺陷之间的相互作用尚未得到充分理解.
研究的目的:
- 调查睡眠质量是否调解大麻使用障碍 (CUD) 和记忆之间的关系.
- 通过睡眠质量来确定性是否会通过睡眠质量来缓和CUD对记忆的影响.
主要方法:
- 对141名患有CUD的成年人和87名对照人群的数据进行了二次分析.
- 评估了睡眠问题 (大麻戒断清单) 和记忆 (sVOLT,sVOLTd,N-back).
- 采用启动调解和调解调解分析.
主要成果:
- 睡眠质量显著调解了CUD和视觉学习记忆 (sVOLT,sVOLTd效率) 之间的关联.
- 睡眠质量差与记忆能力下降相关.
- 性行为并没有调节观察到的关系.
结论:
- 睡眠障碍在CUD和视觉学习记忆之间的联系中起着调解作用.
- 这些发现强调了评估和治疗睡眠障碍在CUD管理中的重要性.
- 突出了CUD中睡眠中断的潜在下游认知后果.
更多相关视频
08:08Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory
Published on: June 18, 2014
27.1K
07:30Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
6.6K
相关概念视频
Understanding Sleep
227
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
227
Insufficient Sleep and Sleep Deprivation
139
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
139
Role of Hippocampus in Memory
218
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
218
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
183
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
183
Substance Use Disorders Affecting Sleep
164
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
164
Role of Neurotransmitters in Memory
521
Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
521
