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对RNA3D结构预测方法的比较分析:用于对RNA-干相互作用的增强建模

Chandran Nithin1,2, Sebastian Kmiecik2, Roman Błaszczyk1

  • 1Molecure SA, 02-089 Warsaw, Poland.

Nucleic acids research
|June 25, 2024
PubMed
概括

预测RNA3D结构是药物设计的关键. 机器学习方法在全球折叠中表现出色,而其他方法更好地捕捉局部交互,两者都显示出对RNA-连接体结合位点建模的希望.

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