德斯梅特膜内皮质角质整形用于内皮质在初级角度关闭怀疑的失败
Eva Roy-Chowdhury1, Maximilian P M Angerer, Ursula Schlötzer-Schrehardt
1Department of Ophthalmology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Cornea
|June 25, 2024
概括
德塞梅特膜内皮质角膜整形 (DMEK) 是一种可行的治疗方法,用于内皮功能衰竭的主要角度闭合疑似 (PACS) 眼睛. 这种角膜移植手术的成功率很高,改善了角膜厚度和视力敏度.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 主要角关闭嫌疑人 (PACS) 可以导致内皮功能障碍.
- 内皮细胞衰竭需要角膜移植以恢复视力.
研究的目的:
- 评估Descemet膜内皮质角膜整形手术 (DMEK) 的可行性和结果,主要角度关闭疑似 (PACS) 的眼睛.
- 在这个特定的患者群体中,在DMEK后评估视觉敏度,角膜厚度和内皮细胞密度.
主要方法:
- 一个回顾性病例系列,包括9名患者的10只眼睛,这些患者因PACS相关的内皮功能衰竭而接受DMEK治疗.
- 收集的数据包括DMEK成功率,最佳校正视敏度,前腔深度,中角膜厚度和内皮细胞密度.
- 平均随访时间为16个月.
主要成果:
- 在10个眼睛中,DMEK在9个眼睛中取得了成功,其中一个眼睛由于移植失败而需要重复手术.
- 观察到中部角膜厚度显著减少 (849微米到517微米,P=0.002).
- DMEK 单独进行或与白内障手术相结合.
结论:
- 德塞梅特膜内皮质角膜整形术 (DMEK) 是一种可行的手术选择,用于初级角关闭疑似 (PACS) 眼睛内皮功能衰竭.
- 建议采取分阶段的方法,使用DMEK然后进行白内障手术,当视力差阻止同时提取白内障时.
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