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Updated: Jun 23, 2025

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

Published on: June 29, 2016

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大骨B细胞阻断了脂酶A2受体与其抗体之间的结合

Zixin Feng1, Fu-Sheng Guo2, Qian Wang3

  • 1Renal Division, Peking University First Hospital, Beijing, China; Institute of Nephrology, Peking University, Beijing, China; Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China; Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing, China.

Bioorganic & medicinal chemistry
|June 25, 2024
PubMed
概括

研究人员选了4000多种化合物,以寻找脂酶A2受体 (PLA2R) 抗体的抑制剂,这是膜性病的关键因素. 巨骨B显示有前途,减少PLA2R-抗体结合,并保护人体细胞免受伤害.

关键词:
抗原-抗体相互作用药物发现 药物发现膜性脏病是一种膜性脏病.自然产品是一种自然产品.这就是 PLA2R.

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