暴露于颗粒物和儿童睡眠障碍 - 在中国三个省份进行的一项大型研究
Zhao-Huan Gui1, Joachim Heinrich2, Zhengmin Min Qian3
1Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Environment international
|June 25, 2024
概括
长期暴露于细颗粒物 (PM2.5和PM1) 与儿童睡眠障碍的增加有关. 这些关联因地区而异,在东南地区观察到更强烈的影响.
科学领域:
- 环境健康 环境健康
- 儿科睡眠医学 儿科睡眠医学
- 流行病学 流行病学
背景情况:
- 关于长期暴露于环境颗粒物 (PM) 和儿童睡眠障碍之间的联系的证据有限.
- 颗粒物,特别是PM2.5和PM1,是常见的空气污染物,具有潜在的健康影响.
研究的目的:
- 调查长期暴露于PM2.5和PM1与儿童睡眠障碍的患病率之间的联系.
- 探索这些协会的区域差异.
主要方法:
- 在中国14个城市 (2012-2018) 进行了一项以人口为基础的177,263名6-18岁儿童的横截面调查.
- 基于卫星的时空建模估计了四年平均PM2.5和PM1暴露量.
- 用家长完成儿童睡眠障碍量表和通用线性混合模型进行分析.
主要成果:
- 对PM2.5和PM1的长期暴露与全球睡眠障碍和亚型的概率增加有关.
- 在PM2.5和PM1中增加10μg/m3与相应的1.24和1.31的几率比率有关.
- 与东北和西北相比,东南地区的关联比东南地区更强,东南地区的PM1估计高于PM2.5.
结论:
- 长期暴露于PM2.5和PM1独立地与儿童睡眠障碍的风险更高有关.
- 观察到的颗粒物暴露和儿童睡眠障碍之间的关联显示出显著的地理异质性.
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