TLR9激素有差异性影响人类NK细胞介导的直接杀死和抗体依赖的细胞介导的细胞毒性

Anna R Mahr1, Maia M C Bennett-Boehm1,2, Frederik H Rothemejer3,4

  • 1Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA.

Scientific reports
|June 25, 2024
PubMed
概括

收费类受体9 (TLR9) 激素增强自然杀手 (NK) 细胞直接杀死瘤细胞,但不是抗体依赖的细胞中介细胞毒性 (ADCC). 这可能是由于TLR9激活后NK细胞的CD16表达减少.

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