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适应性选择在G6PD和糖尿病并发症的差异

Joseph H Breeyear1,2,3, Jacklyn N Hellwege3,4,5, Philip H Schroeder6,7,8,9

  • 1Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA.

Nature medicine
|June 25, 2024
PubMed
概括

葡萄糖-6-酸脱酶缺乏症 (G6PDdef) 与非洲血统个体中糖尿病并发症率较高有关. 一种特定的G6PDdef变异 (rs1050828-T) 增加了视网膜病变的风险,突出了基因型调整糖尿病管理的需要.

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