慢性子宫内膜炎在经宫切除子宫内膜聚后增加了子宫内膜聚的复发风险:一项前性研究
Jing Huang1,2, Xiao You1,2, Zijun Zhao1,2
1Department of Obstetrics and Gynecology, Affiliated Hospital of North Sichuan Medical College, No 63, Wenhua Road, Nanchong, 637000, China.
BMC women's health
|June 25, 2024
概括
慢性子宫内膜炎 (CE) 在绝经前妇女手术后显著增加子宫内膜聚 (EP) 的复发. 在EP中,较高的CE严重程度和CD138表达与更高的复发风险相关.
科学领域:
- 妇科 妇科 妇科 妇科
- 生殖医学 生殖医学
- 病理学 病理学 病理学
背景情况:
- 慢性子宫内膜炎 (CE) 是一种影响子宫内膜的疾病.
- 子宫内膜聚 (EP) 是子宫中常见的生长.
- 治疗后EP的复发可能会影响妇女的生殖健康.
研究的目的:
- 为了确定慢性子宫内膜炎 (CE) 是否会影响绝经前妇女子宫内膜聚 (EP) 的复发.
- 为了评估CE严重程度和EP复发之间的关系,经过宫切除子宫内膜聚 (TCRP).
- 调查CD138表达在EP和其复发中的作用.
主要方法:
- 一项针对507名接受TCRP的绝经前妇女的前性研究.
- 根据子宫内膜CD138表达,患者被分为CE和非CE组.
- 一年后的EP复发率在各组之间进行了比较,包括基于EP的CE严重程度和CD138表达的子组.
主要成果:
- 在1年后的EP复发在CE组 (25.6%) 与非CE组 (10.4%) 相比显著更高.
- 复发率与CE严重程度 (轻度CE:18.7%,严重CE:34.5%) 以及表达CD138的EP (30.5%与6.5%) 相比增加.
- 调整后的几率比率表明,CE患者的EP复发风险增加了3.10倍,严重的CE和CD138阳性EP的风险更高.
结论:
- 慢性子宫内膜炎在绝经前妇女中大大提高了子宫内膜聚体在TCRP后复发的风险.
- EP复发的风险与慢性子宫内膜炎的严重程度正相关.
- 在子宫内膜聚体内CD138表达是增加复发风险的指标.
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