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Updated: Jul 10, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 15, 2010

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亚型C特异性氨基酸变异对HIV-1 Tat-TAR相互作用的影响:从分子建模和动态学的见解

Piwai T Gotora1, Keaghan Brown2, Darius R Martin2,3

  • 1Human Metabolomics, North-West University, Potchefstroom, South Africa.

Virology journal
|June 25, 2024
PubMed
概括

艾滋病毒-1 Tat亚型C变体显示改变了对TAR的结合,影响病毒复制和神经毒性. 特定突变显著影响Tat-TAR相互作用,提供潜在的治疗点.

关键词:
与艾滋病毒相关的神经认知障碍分子对接是分子对接.分子动态模拟分子动态模拟分子建模分子建模亚型B 亚型B 亚型B 亚型亚型C 亚型C 亚型C 亚型这种多态度的多态度是 Tat.

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