希腊儿科和新生儿中枢线相关血流感染的可归因死亡率
Sofia Karagiannidou1, Georgia Kourlaba1,2, Theoklis Zaoutis1,3
1Center for Clinical Epidemiology and Outcomes Research, Non-Profit Civil Partnership, Athens, Greece.
Journal of pediatric intensive care
|June 26, 2024
概括
中枢线相关的血液感染 (CLABSI) 在希腊儿科患者中显著增加死亡率. 实施强有力的感染预防策略至关重要,以减少这些在医院获得的感染,并改善患者的治疗结果.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
背景情况:
- 中枢线相关血流感染 (CLABSI) 是儿科患者在医院获得的感染的主要原因.
- 这些感染显著影响患者的结果,包括死亡率.
- 估计可归因死亡率对于了解CLABSI的真正负担至关重要.
研究的目的:
- 确定与希腊儿科和新生儿患者的CLABSI相关的可归因死亡率.
- 量化与没有CLABSI患者相比,患有CLABSI患者的死亡风险增加.
主要方法:
- 在希腊的两个三级儿科医院进行了一项追溯匹配队列研究.
- 符合条件的患者包括从2012年6月到2015年6月在NICU,PICU,血液学/瘤学和骨髓移植单位的住院患者.
- 确诊的CLABSI患者与非CLABSI患者根据医院,单位和之前住院时间进行了1:1匹配.
主要成果:
- 对CLABSI的总体可归因死亡率为13.8%.
- 与非CLABSI患者 (9.6%) 相比,患有CLABSI的患者的死亡率明显更高 (23.4%).
- CLABSI患者死亡的可能性是病人的四倍 (OR=4.29).
结论:
- CLABSI导致希腊儿科患者的死亡率增加.
- 这些发现强调了在医疗保健机构中需要有效的感染预防策略的迫切需要.
- 减少CLABSI对于改善脆弱儿科群体的生存和结果至关重要.
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