在接受氧气治疗的儿科重症监护病房患者中高氧化
Azadeh R Fayazi1, Matteo Sesia2, Kanwaljeet J S Anand1
1Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Palo Alto, California, United States.
Journal of pediatric intensive care
|June 26, 2024
概括
接受氧气治疗的儿科重症监护室 (PICU) 患者经常经历长时间的高氧化症. 这种以高血氧水平为特征的疾病,在他们的治疗过程中发生了很大一部分,并可能导致器官损伤.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 呼吸系统生理学 呼吸系统生理学
- 在重症监护室的患者安全.
背景情况:
- 超治疗性氧气水平可能导致器官毒性.
- 儿科重症监护室 (PICU) 患者中高氧化血的患病率和严重程度尚不清楚.
研究的目的:
- 确定在 PICU 接受氧气治疗的儿科患者中高氧化血的患病率和持续时间.
主要方法:
- 回顾18岁以下入院到36张床位的PICU的患者的回顾性图表审查.
- 纳入标准:住院时间≥24小时,氧气治疗时间≥12小时,至少一次动脉血液气体测量.
- 收集了有关氧气治疗持续时间,高氧化症发生率和氧气输送参数的数据.
主要成果:
- 在5,251名PICU患者中,有614人符合纳入标准.
- 患者在PICU治疗时间的91%接受了氧气治疗,并且在该时间的65%处于高氧化状态.
- 平均高氧化症持续时间为每名患者38小时;只有1.1%的人没有高氧化症. 平均PaO2为108.7 torr,其中42.1%>100 torr.
结论:
- 接受氧治疗的PICU患者通常会出现长期高氧化,即使吸入氧气 (FiO2) 分数相对较低.
- 这种持续的高氧化可能会导致严重病症儿童持续的器官损伤.
- 需要进一步的研究来优化氧气治疗和减轻风险.
相关概念视频
Respiratory Assessment: Purpose and Indications
1.1K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.1K
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
195
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
195
Oxygen Transport in the Blood
2.6K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
2.6K
Acute Respiratory Failure-II
201
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
201
Special considerations while measuring oxygen saturation
575
Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
575
Physiological Control of Respiration
2.0K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
2.0K


