医疗保健资源利用与间歇性口服皮质类固醇处方模式在喘中相关
Trung N Tran1, Heath Heatley2, Arnaud Bourdin3
1BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD, USA.
Journal of asthma and allergy
|June 26, 2024
概括
经常使用口服皮质类固醇 (OCS) 治疗喘会增加医疗保健资源利用率和成本. 更好的喘管理对于减少对OCS的依赖至关重要.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 口服皮质类固醇 (OCS) 在喘管理中的使用与显著的医疗资源利用率 (HCRU) 和成本有关.
- 有限的研究存在于间歇性OCS处方模式对HCRU和成本的影响.
研究的目的:
- 研究间歇性口服皮质类固醇 (OCS) 处方模式与医疗保健资源利用率 (HCRU) 和喘患者的成本之间的关联.
- 为了比较使用间歇性OCS和非处方OCS的患者之间的HCRU和成本.
主要方法:
- 一项历史性的英国队列研究 (2008-2019) 分析了与医院情节统计相关的初级保健记录.
- 间歇性OCS喘患者 (≥4年) 按处方频率分类 (一次性,不常见,频繁).
- 与非OCS用户匹配1:1以比较HCRU和相关成本.
主要成果:
- 与非OCS使用者相比,间歇性OCS使用与较高的非呼吸HCRU (GP访问,住院,住院时间) 和成本有关.
- 频繁的间歇性OCS处方模式显示了最高的HCRU和成本率.
- 观察到剂量与反应的关系,在经常处方组的成本最高.
结论:
- 间歇性使用OCS,特别是频繁的模式,显著增加HCRU和相关的医疗保健支出.
- 需要改进喘管理策略,以尽量减少对初级保健中间歇性OCS的依赖.
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