儿童COVID-19对心血管的影响
Meredith Cg Broberg1, Monty B Mazer1, Ira M Cheifetz1
1Division of Cardiac Critical Care, UH Rainbow Babies & Children's Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.
Annals of the Academy of Medicine, Singapore
|June 26, 2024
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 可以导致儿童的心血管疾病,包括心肌炎和心律不整. 虽然大多数儿童完全康复,但需要进一步的研究来了解长期风险.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 传染性疾病 传染性疾病
- 心血管医学 心血管医学
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染,导致冠状病毒疾病2019 (COVID-19),主要导致呼吸衰竭,但也影响心血管系统.
- 儿童的心脏表现包括心肌炎,心心膜炎,心律失常,冠状动脉瘤和心肌病,可能导致心脏性休克和多系统器官衰竭.
研究的目的:
- 在儿科人口中审查SARS-CoV-2的心脏表现.
- 检查与急性COVID-19相关的心血管疾病,儿童多系统炎症综合征 (MIS-C) 和mRNA COVID-19疫苗.
- 针对儿科运动员的特殊考虑,并在COVID-19后恢复比赛协议.
主要方法:
- 与COVID-19,MIS-C和疫苗相关的儿童心血管疾病的范围审查.
- 对儿童心脏功能障碍的查,评估,监测和实验室检测的分析.
- 对MIS-C的治疗策略和对严重的COVID-19心脏并发症的支持性护理的审查.
主要成果:
- 患有急性COVID-19的儿童需要进行心脏查,患有心律不整或心肌炎症状的儿童需要进一步评估.
- 对于住院患者,建议进行持续的心脏监测和特定的实验室测试 (热素,BNP/pro-BNP).
- 心声图和心脏MRI帮助评估心脏功能和结构. 组合疗法 (IVIG和葡萄糖皮质类药物) 对MIS-C有效.
结论:
- 心血管疾病是儿童SARS-CoV-2感染的重要特征.
- 大多数患有COVID-19心脏病的儿科患者在没有持久性功能障碍的情况下完全康复.
- 长期研究对于评估与SARS-CoV-2变种和COVID-19相关的心脏功能障碍相关的心血管风险至关重要.
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