卵子在冰上:探索女性选择性卵子冷方面的进展
Judith Ong1, Joyce Mathew1, Mahesh Choolani1
1Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Annals of the Academy of Medicine, Singapore
|June 26, 2024
概括
选择性卵子冷 (EEF) 是一个可行的选择,希望保持生育能力的妇女,由于卵子质量下降后32. 最佳的结发生在37岁之前,根据年龄推特定的卵细胞数量,以实现成功的活产.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 辅助生殖技术 辅助生殖技术
背景情况:
- 女性生育能力在32岁以后显著下降,在37岁以后加速.
- 延迟结婚和第一胎年龄增加了对生育保护选择的需求.
- 选择性卵子冷 (EEF),或卵子冷保存 (OC),现在可用于与年龄相关的生育能力下降.
研究的目的:
- 审查关于EEF关于生殖结果和安全的文献.
- 为咨询年轻单身妇女生育保护的临床医生提供指导.
主要方法:
- 对EEF发表的研究进行系统检查.
- 分析影响最佳年龄,卵细胞产量,协议,冷保存技术和怀孕风险的因素.
主要成果:
- 建议在37岁之前进行EEF.
- 14,15和26个成熟卵子被预测为70%的活产机会所必需的,分别在30-34,35-37岁和38岁以上.
- 与缓慢冷相比,卵细胞玻璃化改善了结果,对母亲或儿童没有增加的风险.
结论:
- 单身妇女的EEF是一种可行的生育保护选择.
- 虽然EEF在财务上很重要,但如果使用卵细胞,则可以获得值得的回报.
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