儿童因避免限制性食物摄入障碍引起的维尼克脑病:基于案例的审查
Ida Turrini1, Clotilde Guidetti1, Ilaria Contaldo1
1Pediatric Neurology Unit, Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Diseases (Basel, Switzerland)
|June 26, 2024
概括
韦尼克脑病 (WE) 是一种严重的胺缺乏症,可以先于儿童的ARFID等饮食障碍. 在儿童病例中,早期识别和治疗导致神经系统完全恢复.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 精神病学是一个精神病学.
背景情况:
- 沃尼克脑病 (Wernicke encephalopathy,简称WE) 是一种由胺缺乏症引起的关键神经精神疾病.
- 它的表现可能很复杂,难以诊断,特别是在儿科患者群体中.
- 限制营养和减肥可能是关键指标.
研究的目的:
- 要突出避免限制性食物摄入障碍 (ARFID) 和维尼克脑病 (WE) 在儿科病例中的关联.
- 强调在儿童出现神经症状暗示WE时考虑ARFID的重要性.
主要方法:
- 一个8岁女孩的病例报告出现了严重的吐,体重减轻和神经症状 (动力不良的行走,阴影,困惑).
- 诊断工具包括临床评估,脑MRI揭示特征性乳头和周水管T2信号,以及低血清胺水平.
- 治疗包括提氨酸补充剂,认知行为疗法和ARFID的阿里皮普拉.
主要成果:
- 通过临床,神经放射学和实验室发现证实了WE的诊断.
- 确立了ARFID的联合诊断.
- 患者在治疗一个月后,神经症状和神经征兆完全消失,放射性改善.
结论:
- 避免限制性食物摄入障碍 (ARFID) 可以在韦尔尼克脑病变 (WE) 之前出现.
- 在患有异常神经病变或食困难的儿科患者中,应考虑这种关联.
- 及时诊断和综合治疗对于有利的结果至关重要.
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