死亡率和COVID感染:10个月后死亡率的预测因素
Víctor Vera-Delgado1, Dácil García-Rosado1, Onán Pérez-Hernández1
1Servicio de Medicina Interna, Hospital Universitario de Canarias, 38320 San Cristóbal de La Laguna, Spain.
COVID-19患者在住院治疗数月后面临高死亡风险. 诸如高NT-proBNP,尿素,年龄,认知障碍,癌症和白细胞计数等因素可以预测长期死亡率.
科学领域:
- 医学 医学 医学 医学 医学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 住院后的COVID-19患者的长期生存和预后因素仍然不明.
- 在感染数月后评估死亡风险对于患者管理至关重要.
研究的目的:
- 分析住院COVID-19患者在入院后长达10个月的整体死亡率.
- 确定与COVID-19幸存者的长期死亡率相关的独立预后标志物.
主要方法:
- 分析了762名住院COVID-19患者的队列.
- 数据包括临床评估,实验室测试,胸部X射线,人口统计,并发病症和生活方式因素.
- 统计分析确定了独立与死亡率相关的因素.
主要成果:
- 十个月死亡率为25.6%,其中108例在医院死亡,87例在出院后死亡.
- 住院死亡率与高NT-proBNP,尿素升高和年龄较大有关.
- 长期死亡率与高NT-proBNP,尿素升高,认知障碍,癌症和白细胞计数增加有关.
结论:
- 在COVID-19感染后的几个月里,死亡风险仍然存在.
- 离院后的死亡率接近医院内的死亡率.
- 伴随性疾病 (癌症,认知障碍),器官功能障碍和炎症是长期COVID-19死亡率的关键预测因素.
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