通过乳液模板机制形成Pullulan微囊:作为维生素C输送系统的评估
Esther Santamaría1,2, Naroa Lizarreta1, Susana Vílchez3
1Chemical Engineering and Analytical Chemistry Department, Faculty of Chemistry, Universitat de Barcelona, Marti i Franques, 1, 08028 Barcelona, Spain.
Gels (Basel, Switzerland)
|June 26, 2024
概括
这项研究引入了一种创新的方法,使用逆乳液制造Pullulan微囊,非常适合在食品应用中控制释放维生素C等活性成分.
科学领域:
- 食品科学 食品科学 食品科学
- 材料科学 材料科学 材料科学
- 聚合物化学 聚合物化学
背景情况:
- 普卢兰是一种多糖,对食用薄膜有希望,但需要进一步研究水凝和微囊应用.
- 传统的微囊形成方法不适合用于pullulan,因为三甲酸盐 (STMP) 的缓慢凝动力学.
研究的目的:
- 开发和描述Pullulan微囊作为食品工业的活性成分输送系统.
- 研究使用逆水在油乳液作为普鲁兰微囊制造的模板.
主要方法:
- 使用逆水在油乳液作为微囊形成的模板.
- 使用光学显微镜特征化乳液稳定性和滴滴大小.
- 相关的乳液滴滴大小与产生的微囊大小.
- 在不同的pH条件下,评估了微囊作为维生素C释放系统.
主要成果:
- 通过逆乳液模板技术成功生产了普鲁兰微囊.
- 证明了乳液液滴大小和微囊大小之间的相关性,表明一种可行的生产方法.
- 在酸性pH下观察到维生素C的零序释放动力学,在中性pH下观察到菲克的释放动力学.
- 证实维生素C在微囊中14天内对氧化产生有效保护.
结论:
- 逆乳液模板是一种有效的方法,用于生产pullulan微囊.
- 这些微囊表现出受控释放的特性,并为维生素C等活性成分提供显著的保护.
- 开发的Pullulan微囊有可能用于食品工业的创新应用,特别是在活性成分输送系统中.
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