来自植物的化合物:一个有前途的工具,预防牙破
Konstantinos Tzimas1, Maria Antoniadou1, Theodoros Varzakas2
1Department of Operative Dentistry, National and Kapodistrian University of Athens, 11521 Athens, Greece.
Current issues in molecular biology
|June 26, 2024
概括
植物衍生化合物对导致牙的细菌,如Streptococcus mutans,具有显著的抗菌作用. 最近的研究强调了它们作为口腔护理中的天然替代品的潜力,其中一些与传统治疗相匹配.
科学领域:
- 口腔健康 口腔健康
- 自然产品 化学 化学
- 微生物学 微生物学
背景情况:
- 越来越多的消费者更喜欢天然口腔护理产品而不是传统药品.
- 关注传统牙科产品对环境和健康的影响.
- 越来越多的人对草药有兴趣,用于预防牙损伤.
研究的目的:
- 审查最近 (2019年至今) 关于用于预防牙损伤的植物性化合物的研究结果.
- 分析植物化学品和草本提取物对口腔病原体的疗效.
- 为了突出当前的趋势,在天然产品的研究,以治理虫.
主要方法:
- 综合文献综述,重点关注从2019年到现在的研究.
- 对植物衍生化合物的体外和体内研究及其对Streptococcus mutans的影响的分析.
- 对抗菌,抗粘附和酶抑制活性数据的评估.
主要成果:
- 许多植物提取物对Streptococcus mutans表现出强烈的抗菌活性,与赫西丁相似.
- 在体内研究表明,在使用植物衍生化合物在食品矩阵 (例如,糖果) 中的儿童中,Streptococcus mutans水平降低.
- 在体外研究证实了植物化合物对Streptococcus mutans的杀菌和细菌静止作用.
结论:
- 植物衍生化合物显示出作为预防牙损伤的天然剂的显著潜力.
- 机制包括直接的抗微生物作用,细胞外酶的抑制和抗粘附性质.
- 进一步的研究对于确认临床应用的安全性和有效性至关重要.
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