暴露于环境空气污染是否会影响妊娠年龄和新生儿体重? - - 一个系统性审查
Bartlomiej Grabowski1, Stepan Feduniw2, Anna Orzel3
1Department of Urology, Military Institute of Medicine, Szaserow 128, 04-349 Warsaw, Poland.
Healthcare (Basel, Switzerland)
|June 26, 2024
概括
像PM2.5这样的空气中的污染物增加了妊娠年龄 (SGA) 和出生时低体重 (TLBW) 婴儿的风险. 减少全球环境污染对于胎儿健康和产前护理至关重要.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 公共卫生 公共卫生
背景情况:
- 空气中的污染物与不良的胎儿生长结果有关,包括怀孕年龄小 (SGA) 和出生时低体重 (TLBW).
- 了解各种污染物的具体影响对于制定有针对性的干预措施至关重要.
研究的目的:
- 系统地审查和批判性地评估有关环境污染与SGA或TLBW发生率之间的联系的现有文献.
- 量化与暴露于特定空气污染物相关的风险.
主要方法:
- 在主要的科学数据库 (PubMed/MEDLINE,科学网,科克莱恩图书馆,EMBASE,谷歌学者) 进行了全面的系统文献搜索.
- 该审查遵守了PRISMA指南,该协议在PROSPERO (ID:CRD42022329624) 中注册.
- 分析了来自69篇选定的论文的数据,重点关注各种污染物的几率比率 (ORs) 以及它们与SGA/TLBW的关联.
主要成果:
- 暴露于≤10微米颗粒物 (PM10) 的OR值为1.138,PM≤2.5微米 (PM2.5) 的OR值为1.338,臭氧 (O3) 的OR值为1.173,二氧化硫 (SO2) 的OR值为1.287,一氧化碳 (CO) 的OR值为1.226.
- 检查挥发性有机化合物 (VOC) 的八项研究都证实它们是SGA或TLBW的风险因素.
- 高风险地区 (城市,近污染源) 的孕妇面临更高的风险.
结论:
- 空气中的污染物显著增加了SGA和TLBW的风险,PM2.5构成重大威胁.
- 确定暴露时间是改善受影响胎儿产前护理和干预措施的关键.
- 全球需要采取紧急的适应措施,以减轻普遍的空气污染,并保护胎儿发育.
关键词:
环境空气污染 环境空气污染一氧化碳 (CO) 是一种二氧化 (NO2) 是一种二氧化.臭氧 (O3) 是一种有毒的物质.颗粒物≤10微米 (PM10) 的颗粒物.颗粒物≤2.5微米 (PM2.5) 的颗粒物.对于妊娠年龄来说很小 (SGA)二氧化硫 (SO2) 是一种二氧化硫.产期低出生体重 (TLBW) 的情况更多相关视频
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