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葡萄牙市场上可用的牛奶和大豆饮料品牌污染了和的致癌风险

Vanda Lopes de Andrade^1,2,3, Iolanda Ribeiro⁴, Ana Paula Marreilha Dos Santos¹

¹Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal.

Journal of xenobiotics

|June 26, 2024

概括

牛奶和大豆饮料中的 (Pb) 和 (Cd) 污染带来致癌风险,尤其对儿童来说. 对牛奶和大豆饮料中的风险做出了重大贡献,需要严格的金属监测.

科学领域:

环境健康环境健康
毒理学毒理学毒理学
食品安全食品安全

背景情况:

之前的研究发现葡萄牙牛奶 (CM) 和大豆饮料 (SB) 中的 (Pb) 和 (Cd) 污染.
这些金属共享致癌机制,表明潜在的添加剂风险.

研究的目的:

评估葡萄牙可用的CM和SB中Pb和Cd摄入的致癌风险.
确定Pb和Cd对整体风险的相对贡献.
在不同消费场景和人口群体中建模累积过剩终身致癌风险 (ELCR).

主要方法:

在各种CM和SB品牌的量化Pb和Cd水平.
计算不同年龄/体重组的慢性每日摄入量.
通过将摄入量乘以癌症斜率因子来估计ELCR.
确定了Pb和Cd对总风险的相对贡献.

主要成果:

五个CM和三个SB品牌存在癌症风险,特别是在儿童中.
最高的ELCR值为CM达到1.75 × 10−4,为SB达到9.12 × 10−5.
在CM中,Pb平均占风险的87.8%,在SB中占54.9%.
在某些消费场景下,针对儿童,青少年和成年人确定了致癌风险.

结论:

在CM和SB中的Pb和Cd污染具有致癌风险,特别是在儿童等弱势群体中.
(Pb) 是这些饮料致癌风险的主要原因之一.
严格监测CM和SB中的金属含量至关重要,因为它们的广泛消费和用于婴儿食品.

关键词:

致癌风险评估致癌风险评估儿童和青少年儿童和青少年牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛奶牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛牛高消费者的高消费者这是一种的混合物.豆类饮料豆类饮料

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