先天性梅毒:一种重新出现但可以预防的感染
Serena Salomè1, Maria Donata Cambriglia1, Giovanna Montesano1
1Division of Neonatology, Department of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy.
Pathogens (Basel, Switzerland)
|June 26, 2024
概括
在全球范围内,先天性梅毒正在增加,导致许多不良出生结果. 通过产前查和治疗进行预防至关重要,但未得到充分利用,阻碍了世界卫生组织的行动.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 孕产妇和儿童的健康
背景情况:
- 先天性梅毒 (CS) 构成了全球健康的重大负担,导致胎儿死亡,死胎,新生儿死亡率和先天性感染.
- 尽管世界卫生组织 (WHO) 的2007年目标是每10万活产婴儿中<50例,但全球CS发病率正在上升,特别是在低收入和中等收入国家.
- 最近的数据显示,每10万活产儿中有473例CS病例,总计661万例,每年有35万5千例不良分娩结果.
研究的目的:
- 审查当前的流行病学,传播和怀孕期间梅毒的治疗.
- 探索旨在减少梅毒垂直传播的全球战略.
- 确定未能达到世卫组织对先天性梅毒的消除目标的原因.
主要方法:
- 这项研究是对先天性梅毒现有文献和数据的综述.
- 分析了流行病学数据,传播模式和治疗疗效.
- 评估了全球预防计划及其对实现世卫组织目标的影响.
主要成果:
- 出生性梅毒的发病率惊人高,只有6%的不良结果发生在接受产前护理的母亲身上.
- 通过产前查和治疗,有效的预防是可能的,但在全球范围内仍未得到充分实施.
- 尽管有可用的工具和综合计划,先天性梅毒仍然是一个主要的公共卫生问题.
结论:
- 先天性梅毒仍然是一个关键的全球卫生挑战,需要紧急关注和改进的干预策略.
- 加强产前查和及时治疗的努力对于减少不良分娩结果至关重要.
- 解决有效预防计划的障碍是实现世卫组织消除目标的关键.
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