抗微生物有效性和酸盐和酸盐所引起的牙原蛋白损伤
Ediléia Lodi1, Yuri Dal Bello1, Karen Barea de Paula Duarte2
1Universidade de Passo Fundo, Passo Fundo, RS, Brasil.
Brazilian dental journal
|June 26, 2024
概括
低酸盐 (Ca(OCl) 2) 和低酸盐 (NaOCl) 对抗Enterococcus faecalis.alis具有相似的抗菌疗效. OCl2表现出与NaOCl相比较的抗菌活性,牙有机基因变化较少,特别是在较低度下.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 生物材料科学 生物材料科学
背景情况:
- 低酸 (NaOCl) 是一种广泛用于牙周内科的灌剂.
- 低化 (Ca(OCl) 2) 是一种具有潜在益处的替代消毒剂.
- 评估这些药物的抗菌活性和实质性对于有效的根管治疗至关重要.
研究的目的:
- 为了比较Ca (OCl) 2和NaOCl在根通道中对Enterococcus faecalis的抗菌疗效.
- 评估Ca (OCl) 2和NaOCl对牙有机基质的影响.
- 为了确定度和接触时间对两种低化物抗菌活性的影响.
主要方法:
- 使用共聚焦激光扫描显微镜 (CLSM) 和活力染色来量化细菌减少.
- 皮克罗西里乌斯染色和光显微镜 (LM) 评估了牙有机基质的改变.
- 被Enterococcus faecalis感染的人类牙被用不同度 (0.5%-6%) 和时间 (15-60s) 的Ca(OCl) 2和NaOCl.
主要成果:
- 在同等度下,Ca ((OCl) 2) 和NaOCl都表现出类似的抗菌活性.
- 较高度 (2.5%和6%) 和较长的接触时间 (30-60s) 导致更大的微生物减少.
- 与NaOCl相比,Ca(OCl) 2对牙有机基质的变化明显较少,特别是在0.5%和2.5%度下.
结论:
- ((OCl) 2具有与NaOCl. 2相比较的抗菌活性.
- 由于减少牙有机基质损伤,Ca ((OCl) 2) 是一种潜在的更安全的替代品.
- 由Ca(OCl) 2引起的原损伤依赖于度,这表明最优化使用是可能的.
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