宫脊髓炎骨髓变质症中介的半球间相互作用
Yew Long Lo1,2,3, Ruby Hwang3, Peggy Pei Chee Teng3
1National Neuroscience Institute, Singapore General Hospital, Singapore, Singapore.
概括
患有椎脊髓炎 (CSM) 的患者表现出增长的横导电时间 (TCT),这表明体内有运动控制的补偿机制. 这可能会抵消脊髓损伤后运动皮层刺激性增加.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 脊髓损伤 脊髓损伤 脊髓损伤
背景情况:
- 体促进半球间的通信,这对运动控制至关重要.
- 脊髓病理,如椎脊髓病变 (CSM),可能导致皮质重组.
- 了解这些变化对于管理运动缺陷至关重要.
研究的目的:
- 调查体在CSM患者的运动任务执行中的作用.
- 在CSM患者中使用跨磁刺激 (TMS) 评估跨传导时间 (TCT).
主要方法:
- 将20名CSM患者与19名健康对照进行了比较.
- 测量了ipsilateral和contralateral静音时间,中央电机导电时间和TCT.
- 使用MRI等级评估CSM的严重程度.
主要成果:
- 与对照组相比,CSM患者的上肢和下肢TCT显著增加 (p < 0.001).
- 在CSM患者的上肢双边增加的ipsilateral和contralateral静默期 (p < 0.01).
- 在TCT和中央电机导电时间或CSM严重程度之间没有显著的相关性.
结论:
- 在CSM患者中增加的TCTs可能代表运动控制的补偿机制.
- 这种补偿作用可能涉及体作为抑制途径.
- 它可以抵消脊髓损伤后运动皮层过度刺激.
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