代的定性方法来确定患者报告的手臂淋巴的结果指标的内容验证:LYMPH-Q上肢模块
Manraj N Kaur1, Sylvie D Cornacchi2, Elena Tsangaris3
1Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. mkaur17@bwh.harvard.edu.
Journal of patient-reported outcomes
|June 26, 2024
概括
与乳腺癌相关的淋巴 (BRCL) 显著影响生活质量. LYMPH-Q UE模块是一种新的患者报告结果测量方法,被开发和验证以全面评估女性BRCL.
科学领域:
- 在瘤学瘤学.
- 医学社会学 医学社会学
- 健康 结果 研究 研究 结果
背景情况:
- 乳腺癌相关的淋巴 (BRCL) 是上肢 (UE) 淋巴的常见原因,显著影响患者的生活质量.
- 开发经过验证的患者报告结果指标 (PROM) 对于了解BRCL流行病学和治疗至关重要.
- 现有的PROM可能无法完全捕捉BRCL对患者生活的多方面的影响.
研究的目的:
- 为了证明 LYMPH-Q UE 模块的代内容有效性,一个专为 BRCL.患者设计的 PROM.
- 在 LYMPH-Q UE 模块中开发和验证新的衡量淋巴结胀焦虑和对工作生活影响的尺度.
- 确保PROM捕捉了与UE淋巴瘤患者体验相关的关键概念.
主要方法:
- 一个多步骤的,代的定性方法,使用半结构面试和聚焦小组与诊断为BRCL的妇女.
- 基于定性数据的初始尺度的开发,然后通过患者和临床医生的反进行内容有效性评估.
- 代改进包括概念诱导采访,以识别和整合缺失的概念,如淋巴结胀的担忧和工作影响.
主要成果:
- 开发了六个LYMPH-Q UE尺度,并证明了内容有效性,测量症状,功能,外观,心理影响,信息需求和手臂袖体验.
- 开发了两种新的衡量淋巴的担忧和对工作生活的影响的尺度,并通过随后的定性研究进行了验证.
- 通过15-16名患者的定性数据和12名临床专家的反,证实了所有开发的尺度的内容有效性.
结论:
- LYMPH-Q UE模块是按照国际准则开发的模块化PROM,适用于临床实践,研究和质量改进.
- 它的全面性质和包含与患者相关的概念增强了以患者为中心的共享决策.
- 该研究成功证明了LYMPH-Q UE模块的代内容验证,证实了它对UE淋巴瘤患者的相关性.
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