患有血液性恶性瘤的患者中PICC相关血栓的患病率:系统性审查
Bruna Nogueira Dos Santos1, Beatriz Volpin Gomes Beato2, Elaine Barros Ferreira3
1Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto, SP, Brazil. brunandsantos@hotmail.com.
概括
与外围插入的中央导管 (PICC) 相关的静脉血栓形成会影响9%的患有血液性恶性瘤的患者. 这种患病率可能更高,因为大多数研究都集中在症状病例上.
科学领域:
- 血液学 血液学 血液学
- 血管医学 血管医学
- 在瘤学瘤学.
背景情况:
- 血液性恶性瘤增加了静脉血栓栓塞的风险.
- 外围插入的中央导管 (PICC) 对于治疗至关重要,但与血栓形成有关.
- 了解这群人中与PICC相关的静脉血栓的患病率对于患者的安全至关重要.
研究的目的:
- 为了确定与PICC相关的静脉血栓塞在患有血液性恶性瘤的患者中的患病率.
- 为了综合现有的证据,对这种并发症.
主要方法:
- 观察性研究的系统审查和元分析.
- 在多个数据库 (PubMed,Embase等) 进行的搜索. 和灰色的文学.
- 包括的研究评估了PICC相关的血液病患者的静脉血栓.
主要成果:
- 与PICC相关的静脉血栓的患病率在血液病患者中总体为9%.
- 成人患病率为9%,儿童患病率为6%.
- 大多数包括的研究 (64%) 集中在症状性血栓形成上.
结论:
- 使用PICCs的血液性恶性瘤患者有明显的静脉血栓形成风险.
- 与PICC相关的静脉血栓的真正患病率可能被低估,因为重点关注症状病例.
- 为了更准确的评估,进一步的研究应该考虑无症状血栓形成.
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