从改变精液参数的患者的生物样本中确定电解质和微量元素:一种相关性分析
Ahsanullah Unar1, Hassan Imran Afridi2, Asim Ali3
1Department of Precision Medicine, University of Campania 'L. Vanvitelli', 80138, Naples, Italy. ahsanullah.unar@unicampania.it.
Biological trace element research
|June 26, 2024
概括
像,铜,铁,,和这样的必需营养素对男性生育能力至关重要. 血液,血清和精液中这些元素的缺乏与男性不孕症有关.
科学领域:
- 生殖生物学 生殖生物学
- 营养生物化学 营养生物化学
- 环境健康 环境健康
背景情况:
- 像 (Ca),铜 (Cu),铁 (Fe), (Mg), (Se) 和 (Zn) 这样的必需矿物质在精子生成,精子成熟和功能中起着至关重要的作用.
- 这些微量元素的不平衡与男性生殖障碍和病理状况有关.
研究的目的:
- 在不孕男性的生物样本 (血液,血清,精液) 中量化必要的微量和电解质元素 (Ca,Cu,Fe,Mg,Se,Zn).
- 探索这些元素与男性生育状况之间的潜在相关性.
主要方法:
- 原子吸收光谱法用于确定生物样本中的元素度.
- 微波酸消化用于样品制备,使用经过认证的参考材料进行验证.
主要成果:
- 与所有年龄组的肥沃对照人群相比,不孕男性的血液,血清和精液等离子体中Ca,Cu,Fe,Mg,Se和Zn的度明显较低.
- 有证据表明,基本元素缺乏对男性生殖健康有负面影响.
结论:
- 生物流体中基本元素的缺陷可能会对男性不孕症产生重大影响.
- 了解这些生化特征可以为男性生殖健康问题的诊断和治疗策略提供信息,例如oligoasthenoteratozoospermia (OAT).
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