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Updated: Jun 23, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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双重抑制XIIa因子和XIa因子产生一个协同的抗凝效应

Shuai Jiang1, Yitong Li1, Jiali Zhang1

  • 1School of Life Science and Technology, China Pharmaceutical University, Nanjing, China ; and.

Journal of cardiovascular pharmacology
|June 26, 2024
PubMed
概括

结合FXIa和FXIIa抑制剂提供了一个新的抗凝固剂策略. 这种双重抑制在预防血栓形成方面表现出协同效应,而不会增加出血风险,解决了一个关键的未满足需求.

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