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Updated: Jun 23, 2025

Primer-Free Aptamer Selection Using A Random DNA Library
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一个基于c-MET Aptamer的双特异化体Aptamer设计平台,具有可更换冗余区域

Xiangru Zhang1,2, Nan Zhang1,2, Haojun Sun1,3

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.

Chembiochem : a European journal of chemical biology
|June 26, 2024
PubMed
概括

研究人员设计了针对细胞-介质细胞上皮质过渡因子 (c-MET) 的新型嵌合性受体,用于潜在的癌症免疫疗法. 这些双特异性胺体结合c-MET和其他蛋白质,调解T细胞对瘤细胞的粘附.

关键词:
结合结构的结合结构.两种特异性的阿普坦体.在c-Met Met中使用.分子工程 分子工程是指分子工程.承认机制的机制.

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