青少年Sjögren病的眼部表现
Robert Nguyen1,2, Luis Gomez-Castillo1, John A Gonzales2,3
1School of Medicine, University of Washington, Seattle, Washington.
Current opinion in ophthalmology
|June 26, 2024
概括
儿童的青少年斯乔格伦病 (jSjD) 与成人形式不同,在眼睛干燥之前经常出现鼻炎和全身症状. 改进的诊断标准和眼科评估对于准确的jSjD识别和管理至关重要.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 眼科医生 眼科 眼科
- 自免疫性疾病 自免疫性疾病
背景情况:
- 青少年肖格伦病 (jSjD) 是一种罕见的自身免疫性疾病,影响儿童.
- 儿童jSjD的表现往往与成人Sjögren综合征有很大的不同.
- 目前对Sjögren综合征的诊断标准并未为儿科患者群体进行优化.
研究的目的:
- 审查和提高对青少年Sjögren病 (jSjD) 的理解.
- 探索特定于jSjD的诊断标准,眼部表现,眼科检测和管理策略.
- 突出在jSjD研究和临床实践中需要专门针对儿科的方法.
主要方法:
- 文献审查侧重于诊断标准,临床特征和jSjD的管理.
- 对儿科特异性症状的分析和与成人Sjögren综合征的比较.
- 对辅助眼科测试的评估,以诊断在JSjD.
主要成果:
- 患有jSjD的儿童通常会出现复发性鼻炎和前面出现 sicca 症状的腺外症状.
- 现有的成年Sjögren综合征分类标准不足以解决儿科特异性表现.
- 不充分利用眼睛染色分数 (OSS) 和施密尔I等诊断测试可能导致在jSjD中低诊断状结膜炎.
结论:
- 建议在JSjD患者的眼部特征评估时提前转诊眼科医生.
- 在jSjD中治疗状结膜炎的治疗包括滑和抗炎策略.
- 制定普遍接受的jSjD分类标准对于推进研究和患者鉴定至关重要.
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