患有慢性喉喉症状的患者的心理社会负担,有或没有病理性酸性逆流
Kelli Liu1, Amanda J Krause1, Madeline Greytak1
1Division of Gastroenterology and Hepatology, Department of Medicine, University of California San Diego, La Jolla, California, USA.
慢性喉喉症状 (LPS) 与显著的社会心理困扰和焦虑有关,无论是胃食道逆流病 (GERD). 了解这些认知情感因素是有效治疗LPS患者的关键.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 精神病体医学是一种精神病体医学.
背景情况:
- 慢性喉喉症状 (LPS) 通常对标准治疗反应不佳.
- 这可能源于重叠的认知情感过程,影响症状的感知和严重程度.
- 调查心理社会和喉特异性痛苦对于了解治疗耐药性至关重要.
研究的目的:
- 测量慢性LPS患者的心理社会困扰和喉特定的认知困扰.
- 为了比较确诊胃食道逆流病 (GERD) 患者和未确诊患者之间的痛苦水平.
- 确定认知情感因素在慢性喉喉症状中的作用.
主要方法:
- 对患有慢性LPS的成年人进行前性单中心研究.
- 利用经过验证的关于生活质量,症状负担和心理社会困扰的问卷.
- 使用喉认知情感工具 (LCAT) 进行喉高警觉和焦虑评估.
- 目标GERD测试 (内镜/健行监测) 将患者分为GER+和GER-组.
主要成果:
- 分析了129名患者 (66%为女性,平均年龄为54.1).
- 57%的LCAT得分升高,39%的焦虑程度为中度至重度,19%的抑郁程度为中度至重度.
- 在GER+和GER-组之间,LCAT得分或患者报告的结果没有显著差异.
- 在58%的患者中,LCAT,焦虑或抑郁分数升高.
结论:
- 患有慢性LPS的患者表现出高度的过度警,焦虑和心理社会困扰.
- 这些心理因素是普遍存在的,不管有没有病理性GERD.
- 研究结果表明,一个显著的非反流成分有助于慢性LPS的症状负担.
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