在试验性放射学中MethOxyfluraNe (MONITOR):一个随机对照试验
Ross Copping1,2, Paul Balamon1, Marcus Lau1
1Interventional Radiology Department, Liverpool Hospital, Sydney, New South Wales, Australia.
Journal of medical imaging and radiation oncology
|June 26, 2024
概括
在干预性放射学 (IR) 程序中,甲氧化有效降低了疼痛和焦虑. 这项研究发现,甲氧氨酸是一种安全和有益的选择,可以在IR中缓解疼痛和缓解焦虑.
科学领域:
- 医学研究 医学研究
- 麻醉学 麻醉学
- 干预性放射学 干预性放射学
背景情况:
- 手术镇静和疼痛管理在干预放射学 (IR) 中至关重要,但研究不足.
- 甲氧化,以快速发病/消退和良好的安全概况而闻名,已用于轻微的程序.
研究的目的:
- 评估梅托西在干预性放射学 (IR) 程序中的镇静和疼痛管理方面的疗效和安全性.
主要方法:
- 一项随机,双盲,安慰剂对照试验,涉及314名接受portacath插入/移除或固体器官活检的患者.
- 患者通过Penthrox吸入器接受了甲氧化或安慰剂.
- 疼痛和焦虑评分 (视觉模拟尺度) 在手术前,手术期间和手术后进行测量.
主要成果:
- 与安慰剂 (P < 0.001) 相比,在整个过程中,美托西隆组的疼痛和焦虑得分显著降低 (P < 0.001).
- 在手术过程中,甲氧化平均减少了2.5倍的疼痛和1.6倍的焦虑.
- 在梅托西弗兰组中没有报告任何与药物或程序相关的重大不良事件.
结论:
- 甲氧化证明了在选择干预放射学程序中提供止痛和焦虑溶解的安全性和有效性.
- 这些发现支持甲氧化作为一种有价值的选择,用于治疗IR患者的疼痛和焦虑.
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