在子宫缺陷,子宫结,早产等方面的种族和民族差异
Hayley E Miller1, Jonathan A Mayo1, Ravali A Reddy2
1Division of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University, Stanford, California, USA.
Journal of women's health (2002)
|June 26, 2024
概括
在宫缺陷中存在种族差异. 非西班牙裔黑人个人面临的风险最高,而印度和东南亚亚的亚组显示在诊断, cerclage 使用和早产的独特模式,突出需要分类数据.
科学领域:
- 产科和妇科 产科和妇科
- 生殖健康 生殖健康
- 健康差异 在健康上的差异
背景情况:
- 宫缺陷诊断率因种族和民族不同而有所不同.
- 对于亚裔美国人和夏威夷原住民/太平洋岛民 (AANHPI) 亚种群的数据有限.
- 了解这些差异对于公平的产科护理至关重要.
研究的目的:
- 评估各种种族和种族群体的宫衰竭诊断和相关结果.
- 检查AANHPI子组内的分类数据.
- 根据种族和种族来确定特定的产科风险和结果.
主要方法:
- 在加利福尼亚州 (2007-2018) 单子婴儿的回顾性队列研究.
- 分析了超过500万个分娩情况,发现38605例患有宫功能不全.
- 后勤回归模型用于在不同组中比较宫缺陷, cerclage 和早产的几率.
主要成果:
- 与非西班牙裔白人相比,非西班牙裔黑人个体的子宫缺陷,宫和早产的几率最高.
- 印度人表现出子宫缺陷和宫缺陷的可能性增加,但不是早产.
- 东南亚人有最高的早产几率,但没有增加胎率.
结论:
- 在宫衰竭和相关产科结果方面存在显著的种族和民族差异.
- 分类AANHPI数据显示,印度和东南亚人群的风险概况不同.
- 需要量身定制的干预措施和进一步的研究来解决这些发现的差异.
相关概念视频
Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Nondisjunction
3.8K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers. Nondisjunction is common during anaphase I or anaphase II of meiosis. Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
3.8K
Factors Affecting the Risk of Infection
11.6K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.6K
Birth Control Methods
226
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
226
Disorders of the Female Reproductive System
347
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
347
Meiosis vs. Mitosis
55.0K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
55.0K


