通过电诱发化合物作用电位 (eCAP) 获得的激发功能的扩散的临床应用
Katelyn A Berg1, Andrea J DeFreese1, Allyson L Sisler-Dinwiddie1
1Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
概括
电气唤起的复合动能 (eCAP) 激发 (SOE) 的扩散有效地识别了耳植入物 (CI) 电极尖端折叠. 这种方法表明,当图像无法使用时,该方法对手术期间的评估具有前途.
科学领域:
- 听力学 听力学是指听力学.
- 神经外科 神经外科
- 医疗成像医学成像
背景情况:
- 耳植入器 (CI) 手术的目的是为了获得最佳的电极阵列放置,以获得更好的听力结果.
- 精确的电极放置是至关重要的,而手术期间的评估方法是有价值的.
- 电气唤起的复合作用电位 (eCAP) 提供了关于神经反应的生理信息.
研究的目的:
- 评估来自eCAPs的激发传播 (SOE) 的临床实用性.
- 为了确定eCAPSOE是否可以识别电极阵列尖端折叠.
- 为了将eCAP SOE与术后成像和语音识别结果相关联.
主要方法:
- 对272例耳植入物病例的回顾性审查.
- 分析eCAP SOE宽度,电极尖端折叠发生率和CT成像数据.
- eCAP SOE与电极到模块距离,插入深度和语音识别分数的相关性.
主要成果:
- eCAP SOE在检测电极尖端折叠时显示了85.7%的灵敏度,CT证实了这一点.
- 尖端折叠发生在3.1%的病例中,主要是预先曲的阵列.
- eCAP SOE与电极放置因子 (距离,深度) 相相关,但不是标量位置或耳直径.
- 在eCAP SOE和语音识别之间没有发现显著的关系,除了6个月后CNC得分与预先排列的弱负相关性.
结论:
- eCAP SOE是术内成像的可行替代方案,用于识别耳植入物电极阵列尖端折叠.
- 建议对eCAP SOE进行常规的手术内测量,特别是对于预曲电极阵列.
- 虽然eCAP SOE对于折叠检测很有用,但它没有预测本研究中的语音识别结果.
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